Advances in Cytokine and Growth Factor Receptor Signal Transduction in Health and Disease (E08F6A)

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General info

Chapter 1 : Tyrosine kinase receptor signaling (7 hours) - signaling by receptors for FGF, PGDF, VEGF, IGF, EGF (2,5 hours) - structure-function insights (1,5 hours) - aberrant signaling in cancer (1,5 hours) - aberrant signaling in congenital disease of the skeleton (1,5 hours)

Chapter 2 : Serine/threonine kinase receptor signaling (4 hours) - canonical and non-canonical signaling by TGFβ receptors (2,5 hours) - TGFβ signaling in tumor suppression and tumor promotion (1,5 hours)

Chapter 3 : Cytokine receptor signaling (4 hours) - class I and class II cytokine receptors (2,5 hours) - selected applications in the clinic (1,5 hours)

Chapter 4 : Signaling through 7TM-pass receptors (5 hours) - G-coupled receptors (1,5 hours) - Wnt receptors (1,5 hours) - Wnt signaling in cancer (2 hours)

Chapter 5 : Hedgehog signaling (4 hours) - biochemistry and genetics of hedgehog signaling (1,5 hours) - hedgehog signaling and cancer (2,5 hours)

Chapter 6 : Regulation of growth factor receptor signaling (6 hours) - receptor complex assembly (1,5 hours) - non-signaling co-receptors (1,5 hours) - juxtacrine and reverse signaling (1,5 hours) - various routes of endocytic trafficking of receptors lead to different cellular responses (1,5 hours)


Examenvorm

Mode of evaluation : Oral with written preparation

Category : final examination during examination period

Type of evaluation : Closed book

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