Hot Topics in Oncology I (E03N3A)
Cancer develops when gradual irreversible genetic or epigenetic changes accumulate in a cell and transform the cellular proteome in a way that a malignant cellular phenotype can develop. Typical characteristics of the malignant cellular phenotype are: unrestricted and autonomous cell growth, unlimited cell proliferation, resistance to apoptosis, tissue invasion and induction of angiogenesis and genetic instability. Novel and recent insights in cell biology, experimental approach and therapeutic principles of malignant diseases are considered in detail, by means of seminars/journal clubs with the emphasis on personal participation of the students. After this training topic, students are considered to be capable of: -reading and understanding original research articles about cancer independently, placing them in the right context, confronting them with current ruling insights and evaluating them on their limits or merits -presenting research articles on these topics and discussing them in front of an audience of laymen and specialists - writing discussions and evaluations on research articles on these topics - designing a research strategy for specific research inquiries
Form of the exam
Continuous evaluation: presentation/participation
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